Staphylococcus Aureus
is an extremely common and potentially life threatening infection among humans. Staph can be found residing harmlessly on the skin and can be introduced into a surgical site inadvertently.
What is Implant Infection?
Implanted devices are used to control pain, certain bodily functions, and improve quality of life. These devices become contaminated with Staphylococcus Aureus and are introduced into the body when the device is surgically introduced.
Known Treatments
Staph infections are notoriously resistant to antibiotic therapies and must be managed with aggressive therapies. Rifampin is one known antibiotic that can be used to control implant infections.
Combination Treatments
Linezolid is also being used successfully, when Rifampin fails, to treat implant infections. This drug can be used alone, or in combination with Rifampin to treat infection.
Benefits of Combination Treatment
Studies show that the combination therapy prevents the emergence of resistant bacteria that often occurs when Rifampin alone is used to treat quinolone resistant MRSA strains.
Outcome
The combination therapy also shows a 50-60 percent higher overall kill rate than when Rifampin is used alone.
Tags: Staphylococcus Aureus, when Rifampin, combination therapy, Implant Infection, implant infections
